Basic principles of Cell injury and Adaptation:
Introduction
Definitions
Homeostasis
Components and Types of Feedback systems
Causes of cellular injury
Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage)
Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia)
Cell swelling
Intra cellular accumulation
Calcification
Enzyme leakage and Cell Death Acidosis & Alkalosis
Electrolyte imbalance.
Basic mechanism involved in the process of inflammation and repair:
Introduction
Clinical signs of inflammation
Different types of Inflammation
Mechanism of Inflammation – Alteration in vascular permeability and blood flow
Migration of WBC’s
Mediators of inflammation
Basic principles of wound healing in the skin
Pathophysiology of Atherosclerosis.