PHARMACEUTICAL ORGANIC CHEMISTRY - 1 Notes PDF Download | BPharm

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Unit I: Classification, Nomenclature and Isomerism

Syllabus Topics to Learn

Classification of Organic Compounds

Common and IUPAC systems of nomenclature of organic compounds (up to 10 Carbons open chain and carbocyclic compounds). Structural isomerism in organic compounds.

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Unit II: Alkanes, Alkenes and Conjugated dienes*

Syllabus Topics to Learn

Sp3 hybridization in alkanes

Halogenation of alkanes

Uses of paraffins. Stabilities of alkenes

Sp2 hybridization in alkenes. E1 and E2 reactions – Kinetics

Order of reactivity of alkyl halides

Rearrangement of carbocations

Saytzeff’s orientation and evidences. E1 verses E2 reactions

Factors affecting E1 and E2 reactions. Ozonolysis

Electrophilic addition reactions of alkenes

Markownikoff’s orientation

Free radical addition reactions of alkenes

Anti- Markownikoff’s orientation. Stability of conjugated dienes

Diel-Alder

Electrophilic addition

Free radical addition reactions of conjugated dienes

Allylic rearrangement.

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Unit III: Alkyl Halides* And Alcohols*

Syllabus Topics to Learn

Alkyl halides* SN1 and SN2 reactions - kinetics

Order of reactivity of alkyl halides

Stereochemistry and rearrangement of carbocations. SN1 versus SN2 reactions

Factors affecting SN1 and SN2 reactions. Structure and uses of ethyl chloride

Chloroform

Trichloroethylene

Tetrachloroethylene

Dichloromethane

Tetrachloromethane and iodoform. Alcohols*- Qualitative tests

Structure and uses of Ethyl alcohol

Methyl alcohol

Chlorobutanol

Cetosteryl alcohol

Benzyl alcohol

Glycerol

Propylene glycol.

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Unit IV: Carbonyl Compounds* (Aldehydes And Ketones)

Syllabus Topics to Learn

Nucleophilic addition

Electromeric effect

Aldol condensation

Crossed Aldol condensation

Cannizzaro reaction

Crossed Cannizzaro reaction

Benzoin condensation

Perkin condensation

Qualitative tests

Structure and uses of Formaldehyde

Paraldehyde

Acetone

Chloral hydrate

Hexamine

Benzaldehyde

Vanillin

Cinnamaldehyde.

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Unit V: Carboxylic Acids* And Aliphatic Amines*

Syllabus Topics to Learn

Carboxylic Acids*: Acidity of carboxylic acids

Effect of substituents on acidity

Inductive effect and qualitative tests for carboxylic acids

Amide and ester. Structure and Uses of Acetic acid

Lactic acid

Tartaric acid

Citric acid

Succinic acid. Oxalic acid

Salicylic acid

Benzoic acid

Benzyl benzoate

Dimethyl phthalate

Methyl salicylate and Acetyl salicylic acid. Aliphatic amines*: Basicity

Effect of substituent on Basicity. Qualitative test

Structure and uses of Ethanolamine

Ethylenediamine

Amphetamine.

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Subject Overview

Course Code BP202T

Syllabus Status 100% PCI Aligned

Total Units 5 Units

Study Material Notes PDFs

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PHARMACEUTICAL ORGANIC CHEMISTRY - 1

Unit I: Classification, Nomenclature and Isomerism

Syllabus Topics to Learn

Download Notes PDF

Unit Practice Quiz

Explanation Video

Unit II: Alkanes*, Alkenes* and Conjugated dienes*

Syllabus Topics to Learn

Download Notes PDF

Unit Practice Quiz

Explanation Video

Unit III: Alkyl Halides* And Alcohols*

Syllabus Topics to Learn

Download Notes PDF

Unit Practice Quiz

Explanation Video

Unit IV: Carbonyl Compounds* (Aldehydes And Ketones)

Syllabus Topics to Learn

Download Notes PDF

Unit Practice Quiz

Explanation Video

Unit V: Carboxylic Acids* And Aliphatic Amines*

Syllabus Topics to Learn

Download Notes PDF

Unit Practice Quiz

Explanation Video

Subject Overview

Unit II: Alkanes, Alkenes and Conjugated dienes*