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BP502T

INDUSTRIAL PHARMACY - 1

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Unit I: Pre-formulation Studies: Physical And Chemical Properties

Syllabus Topics to Learn

Pre-formulation Studies: Introduction to pre-formulation
Goals and objectives
Study of physicochemical characteristics of drug substances. Physical properties: Physical form (crystal & amorphous)
Particle size
Shape
Flow properties
Solubility profile (pKa, pH, partition coefficient)
Polymorphism. Chemical Properties: Hydrolysis
Oxidation
Reduction
Racemization
Polymerization. BCS classification of drugs & its significance. Application of pre-formulation considerations in the development of solid
Liquid oral and parenteral dosage forms and its impact on stability of dosage forms.

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Subject Overview

Course Code BP502T
Syllabus Status 100% PCI Aligned
Total Units 5 Units
Study Material Notes PDFs
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