Pharmaceutical Chemistry Notes PDF Download | DPharm

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Chapter 1: Introduction To Pharmaceutical Chemistry

Syllabus Topics to Learn

Introduction to Pharmaceutical chemistry: Scope and objectives Sources and types of errors: Accuracy

Precision

Significant figures Impurities in Pharmaceuticals: Source and effect of impurities in Pharmacopoeial substances

Importance of limit test

Principle and procedures of Limit tests for chlorides

Sulphates

Iron

Heavy metals and arsenic.

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Chapter 2: Volumetric And Gravimetric Analysis

Syllabus Topics to Learn

Volumetric analysis: Fundamentals of volumetric analysis

Acid-base titration

Non-aqueous titration

Precipitation titration

Complex metric titration

Redox titration Gravimetric analysis: Principle and method

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Chapter 3: Inorganic Pharmaceuticals: Pharmaceutical 7 Formulations, Market Preparations, Storage Conditions And Uses

Syllabus Topics to Learn

Inorganic Pharmaceuticals: Pharmaceutical 7 formulations

Market preparations

Storage conditions and uses of Haematinics: Ferrous sulphate

Ferrous fumarate

Ferric ammonium citrate

Ferrous ascorbate

Carbonyl iron Antacids: Aluminium hydroxide gel

Magnesium hydroxide

Magaldrate

Sodium bicarbonate

Calcium Carbonate Anti-microbial agents: Silver Nitrate

Ionic Silver

Chlorhexidine Gluconate

Hydrogen peroxide

Boric acid

Bleaching powder

Potassium permanganate Dental products: Calcium carbonate

Sodium fluoride

Denture cleaners

Denture adhesives

Mouth washes Medicinal gases: Carbon dioxide

Nitrous oxide

Oxygen

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Chapter 4: Introduction To Nomenclature

Syllabus Topics to Learn

Introduction to nomenclature of organic chemical systems with particular reference to heterocyclic compounds containing up to Three rings

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Chapter 5: Study of The of Medicinal Compounds:Drugs Acting on Central Nervous System

Syllabus Topics to Learn

Study of the following category of medicinal compounds with respect to classification

Chemical name

Chemical structure (compounds marked with*) uses

Stability and storage conditions

Different types of formulations and their popular brand names Drugs Acting on Central Nervous System Anaesthetics: Thiopental Sodium*

Ketamine Hydrochloride*

Propofol Sedatives and Hypnotics: Diazepam*

Alprazolam*

Nitrazepam

Phenobarbital* Antipsychotics: Chlorpromazine Hydrochloride*

Haloperidol*

Risperidone*

Sulpiride*

Olanzapine

Quetiapine

Lurasidone Anticonvulsants: Phenytoin*

Carbamazepine*

Clonazepam

Valproic Acid*

Gabapentin*

Topiramate

Vigabatrin

Lamotrigine Anti-Depressants: Amitriptyline Hydrochloride*

Imipramine Hydrochloride*

Fluoxetine*

Venlafaxine

Duloxetine

Sertraline

Citalopram

Escitalopram

Fluvoxamine

Paroxetine

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Chapter 6: Study of Medicinal Compounds: Drugs Acting on Autonomic Nervous System

Syllabus Topics to Learn

Study of the following category of medicinal compounds with respect to classification

Chemical name

Chemical structure (compounds marked with*) uses

Stability and storage conditions

Different types of formulations and their popular brand names Drugs Acting on Autonomic Nervous System Sympathomimetic Agents (Adrenergic Agonists) Direct Acting Agents : Nor-epinephrine

* Phenylephrine

Terbutaline

Naphazoline

* Epinephrine

Dopamine

* Salbutamol

Tetrahydrozoline Indirect Acting Agents : Hydroxyamphetamine

Pseudoephedrine Sympathomimetic Agents (Adrenergic Agonists) Mixed Acting Agents : Ephedrine

Metaraminol Adrenergic Antagonists (Sympatholytic Agents) Alpha Adrenergic Blockers : Tolazoline

Phentolamine

Phenoxybenzamine

Adrenergic Antagonists (Sympatholytic Agents) Beta Adrenergic Blockers : Propranolol

* Ateolol

* Carvedilol Cholinergic Drugs And Related Agents (PARASYMPATHOMIMETRIC ) Direct Acting Agents Acetylcholine

* Carbachol

Cholinesterase Inhibitors (Indirect Acting Agents) Neostigmine

* Edrophonium chloride

Tacrine hydrochloride

Echothiophate iodide. Cholinergic Blocking Agents (Cholinergic Antagonists) Atropine sulphate

* Ipratropium bromide. Synthetic Cholinergic Blocking Agents Tropicamide

Cyclopentolate hydrochloride

Clidinium bromide

And Dicyclomine hydrochloride. *

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Chapter 7: Study of Medicinal Compounds: Drugs Acting on Cardiovascular System

Syllabus Topics to Learn

Study of the following category of medicinal compounds with respect to classification

Chemical name

Chemical structure (compounds marked with*) uses

Stability and storage conditions

Different types of formulations and their popular brand names Drugs Acting on Cardiovascular System Anti-Arrhythmic Drugs: Quinidine Sulphate

Procainamide Hydrochloride

Verapamil

Phenytoin Sodium*

Lidocaine Hydrochloride

Lorcainide Hydrochloride

Amiodarone and Sotalol Anti-Hypertensive Agents: Propranolol*

Captopril*

Ramipril

Methyldopate Hydrochloride

Clonidine Hydrochloride

Hydralazine Hydrochloride

Nifedipine

Antianginal Agents: Isosorbide Dinitrate

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Chapter 8: Diuretics

Syllabus Topics to Learn

Study of the following category of medicinal compounds with respect to classification

Chemical name

Chemical structure (compounds marked with*) uses

Stability and storage conditions

Different types of formulations and their popular brand names Diuretics Acetazolamide

Frusemide*

Bumetanide

Chlorthalidone

Benzthiazide

Metolazone

Xipamide

Spironolactone

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Chapter 9: Hypoglycemic Agents

Syllabus Topics to Learn

Study of the following category of medicinal compounds with respect to classification

Chemical name

Chemical structure (compounds marked with*) uses

Stability and storage conditions

Different types of formulations and their popular brand names Hypoglycemic Agents: Insulin and Its Preparations

Metformin*

Glibenclamide*

Glimepiride

Pioglitazone

Repaglinide

Gliflozins

Gliptins

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Chapter 10: Analgesic And Anti-Inflammatory Agents

Syllabus Topics to Learn

Chapter-10 Study of the following category of medicinal compounds with respect to classification

Chemical name

Chemical structure (compounds marked with*) uses

Stability and storage conditions

Different types of formulations and their popular brand names Analgesic And Anti-Inflammatory Agents Analgesic And Anti-Inflammatory Agents: Morphine Analogues

Narcotic Antagonists; Nonsteroidal AntiInflammatory Agents (NSAIDs) – Aspirin*

Diclofenac

Ibuprofen*

Piroxicam

Celecoxib

Mefenamic Acid

Paracetamol*

Aceclofenac

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Chapter 11: Anti-Infective Agents

Syllabus Topics to Learn

Study of the following category of medicinal compounds with respect to classification

Chemical name

Chemical structure (compounds marked with*) uses

Stability and storage conditions

Different types of formulations and their popular brand names Anti-Infective Agents Antifungal Agents: Amphotericin-B

Griseofulvin

Miconazole

Ketoconazole*

Itraconazole

Fluconazole*

Naftifine Hydrochloride Urinary Tract Anti-Infective Agents: Norfloxacin

Ciprofloxacin

Ofloxacin*

Moxifloxacin

Anti-Tubercular Agents: INH*

Ethambutol

Para Amino Salicylic Acid

Pyrazinamide

Rifampicin

Bedaquiline

Delamanid

Pretomanid* Antiviral Agents: Amantadine Hydrochloride

Idoxuridine

Acyclovir*

Foscarnet

Zidovudine

Ribavirin

Remdesivir

Favipiravir Antimalarials: Quinine Sulphate

Chloroquine Phosphate*

Primaquine Phosphate

Mefloquine*

Cycloguanil

Pyrimethamine

Artemisinin Sulfonamides: Sulfanilamide

Sulfadiazine

Sulfamethoxazole

Sulfacetamide*

Mafenide Acetate

Cotrimoxazole

Dapsone*

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Chapter 12: Antibiotics

Syllabus Topics to Learn

Antibiotics Antibiotics: Penicillin G

Amoxicillin*

Cloxacillin

Streptomycin

Tetracyclines: Doxycycline

Minocycline

Macrolides: Erythromycin

Azithromycin

Miscellaneous: Chloramphenicol* Clindamycin

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Chapter 13: Anti-Neoplastic Agents

Syllabus Topics to Learn

Anti-Neoplastic Agents Anti-Neoplastic Agents: Cyclophosphamide*

Busulfan

Mercaptopurine

Fluorouracil*

Methotrexate

Dactinomycin

Doxorubicin Hydrochloride

Vinblastine Sulphate

Cisplatin*

Dromostanolone Propionate

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Subject Overview

Course Code BP101T

Syllabus Status 100% PCI Aligned

Total Units 13 Units

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